New Brain Implant Thinner Than Hair

Calendar February 21, 2023 | Posted by admin

A new technological development could give people the ability to access their devices with only their minds. Precision Neuroscience is introducing its breakthrough in medical science as a benefit for those who have experienced paralysis or other forms of limited mobility.

Precision CEO and co-founder Michael Mager shared in an interview how brain-computer interface (BCI) technology converts thoughts into action. “It’s a direct communication pathway between the brain’s electrical activity and an external device, most often a computer, but it also can be like a prosthetic,” he said. BCIs have been proven to be functional for more than 15 years, but to date have only been implanted in about 40 people — which New York City-based Mager said he considered a “real shame.”

“Our fundamental goal is to change that,” he said. “To take this technology that has been proven to work and roll it out to the hundreds of thousands and eventually millions of people who could benefit enormously from it.” These developments reportedly have been a lifelong venture for Precision‘s chief science officer Ben Rapoport, who has two decades of experience developing BCIs, including during his work as a founding member at Neuralink.

Source: https://precisionneuro.io/
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Brain Implant Could Be the Next Computer Mouse

Calendar February 1, 2023 | Posted by admin

Eight years ago, a patient lost her power of speech because of ALS, or Lou Gehrig’s disease, which causes progressive paralysis. She can still make sounds, but her words have become unintelligible, leaving her reliant on a writing board or iPad to communicate.

Now, after volunteering to receive a brain implant, the woman has been able to rapidly communicate phrases like “I don’t own my home” and “It’s just tough” at a rate approaching normal speech.

That is the claim in a paper published over the weekend on the website bioRxiv by a team at Stanford University. The study has not been formally reviewed by other researchers. The scientists say their volunteer, identified only as “subject T12,” smashed previous records by using the brain-reading implant to communicate at a rate of 62 words a minute, three times the previous best.

Philip Sabes, a researcher at the University of California, San Francisco, who was not involved in the project, called the results a “big breakthrough” and said that experimental brain-reading technology could be ready to leave the lab and become a useful product soon.

“The performance in this paper is already at a level which many people who cannot speak would want, if the device were ready,” says Sabes. “People are going to want this.” People without speech deficits typically talk at a rate of about 160 words a minute. Even in an era of keyboards, thumb-typing, emojis, and internet abbreviations, speech remains the fastest form of human-to-human communication.

The new research was carried out at Stanford University. The preprint, published January 21, began drawing extra attention on Twitter and other social media because of the death the same day of its co-lead author, Krishna Shenoy, from pancreatic cancer.

Shenoy had devoted his career to improving the speed of communication through brain interfaces, carefully maintaining a list of records on his laboratory website. In 2019, another volunteer Shenoy worked with managed to use his thoughts to type at a rate of 18 words a minute, a record performance at the time.

Source: https://www.technologyreview.com/

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‘Dancing Molecules’ Successfully Repair Severe Spinal Cord Injuries

Calendar October 4, 2022 | Posted by admin

Northwestern University researchers have developed a new injectable therapy that harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries. In a new study, researchers administered a single injection to tissues surrounding the spinal cords of paralyzed mice. Just four weeks later, the animals regained the ability to walk.

By sending bioactive signals to trigger cells to repair and regenerate, the breakthrough therapy dramatically improved severely injured spinal cords in five key ways: The severed extensions of neurons, called axons, regenerated. Scar tissue, which can create a physical barrier to regeneration and repair, significantly diminished. Myelin, the insulating layer of axons that is important in transmitting electrical signals efficiently, reformed around cells. Functional blood vessels formed to deliver nutrients to cells at the injury site. More motor neurons survived.
After the therapy performs its function, the materials biodegrade into nutrients for the cells within 12 weeks and then completely disappear from the body without noticeable side effects. This is the first study in which researchers controlled the collective motion of molecules through changes in chemical structure to increase a therapeutic’s efficacy.

“Our research aims to find a therapy that can prevent individuals from becoming paralyzed after major trauma or disease,” said Northwestern’s Samuel I. Stupp, who led the study. “For decades, this has remained a major challenge for scientists because our body’s central nervous system, which includes the brain and spinal cord, does not have any significant capacity to repair itself after injury or after the onset of a degenerative disease. We are going straight to the FDA to start the process of getting this new therapy approved for use in human patients, who currently have very few treatment options.”

Stupp is Board of Trustees Professor of Materials Science and Engineering, Chemistry, Medicine and Biomedical Engineering at Northwestern, where he is founding director of the Simpson Querrey Institute for BioNanotechnology (SQI) and its affiliated research center, the Center for Regenerative Nanomedicine.

Source: https://news.northwestern.edu/

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How to Repair Severe Spinal Cord Injuries

Calendar November 16, 2021 | Posted by admin

Northwestern University researchers have developed a new injectable therapy that harnesses “dancing molecules” to reverse paralysis and repair tissue after severe spinal cord injuries. In a new study, researchers administered a single injection to tissues surrounding the spinal cords of paralyzed mice. Just four weeks later, the animals regained the ability to walk.

By sending bioactive signals to trigger cells to repair and regenerate, the breakthrough therapy dramatically improved severely injured spinal cords in five key ways: (1) The severed extensions of neurons, called axons, regenerated; (2) scar tissue, which can create a physical barrier to regeneration and repair, significantly diminished; (3) myelin, the insulating layer of axons that is important in transmitting electrical signals efficiently, reformed around cells; (4) functional blood vessels formed to deliver nutrients to cells at the injury site; and (5) more motor neurons survived. After the therapy performs its function, the materials biodegrade into nutrients for the cells within 12 weeks and then completely disappear from the body without noticeable side effects.

 

A new injectable therapy forms nanofibers with two different bioactive signals (green and orange) that communicate with cells to initiate repair of the injured spinal cord.

“Our research aims to find a therapy that can prevent individuals from becoming paralyzed after major trauma or disease,” said Northwestern’s Samuel I. Stupp, who led the study. “For decades, this has remained a major challenge for scientists because our body’s central nervous system, which includes the brain and spinal cord, does not have any significant capacity to repair itself after injury or after the onset of a degenerative disease. We are going straight to the FDA to start the process of getting this new therapy approved for use in human patients, who currently have very few treatment options.”

Stupp is Board of Trustees Professor of Materials Science and Engineering, Chemistry, Medicine and Biomedical Engineering at Northwestern, where he is founding director of the Simpson Querrey Institute for BioNanotechnology (SQI) and its affiliated research center, the Center for Regenerative Nanomedicine.

The research has been published in the journal Science. The study is now available online.

Source: https://news.northwestern.edu/

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