Quantum Entanglement Wins 2022’s Nobel Prize

For generations, scientists argued over whether there was truly an objective, predictable reality for even quantum particles, or whether quantum “weirdness” was inherent to physical systems. In the 1960s, John Stewart Bell developed an inequality describing the maximum possible statistical correlation between two entangled particles: Bell’s inequality. But certain experiments could violate Bell’s inequality, and these three pioneers —  John Clauser, Alain Aspect, and Anton Zeilinger — helped make quantum information systems a bona fide science.

There’s a simple but profound question that physicists, despite all we’ve learned about the Universe, cannot fundamentally answer:What is real?” We know that particles exist, and we know that particles have certain properties when you measure them. But we also know that the very act of measuring a quantum state — or even allowing two quanta to interact with one another — can fundamentally alter or determine what you measure. An objective reality, devoid of the actions of an observer, does not appear to exist in any sort of fundamental way.

But that doesn’t mean there aren’t rules that nature must obey. Those rules exist, even if they’re difficult and counterintuitive to understand. Instead of arguing over one philosophical approach versus another to uncover the true quantum nature of reality, we can turn to properly-designed experiments. Even two entangled quantum states must obey certain rules, and that’s leading to the development of quantum information sciences: an emerging field with potentially revolutionary applications. 2022’s Nobel Prize in Physics was just announced, and it’s awarded to John Clauser, Alain Aspect, and Anton Zeilinger for the pioneering development of quantum information systems, entangled photons, and the violation of Bell’s inequalities. It’s a Nobel Prize that’s long overdue, and the science behind it is particularly mind-bending.

There are all sorts of experiments we can perform that illustrate the indeterminate nature of our quantum reality.

Place a number of radioactive atoms in a container and wait a specific amount of time. You can predict, on average, how many atoms will remain versus how many will have decayed, but you have no way of predicting which atoms will and won’t survive. We can only derive statistical probabilities.
Fire a series of particles through a narrowly spaced double slit and you’ll be able to predict what sort of interference pattern will arise on the screen behind it. However, for each individual particle, even when sent through the slits one at a time, you cannot predict where it will land.
Pass a series of particles (that possess quantum spin) through a magnetic field and half will deflect “up” while half deflect “down” along the direction of the field. If you don’t pass them through another, perpendicular magnet, they’ll maintain their spin orientation in that direction; if you do, however, their spin orientation will once again become randomized.
Certain aspects of quantum physics appear to be totally random. But are they really random, or do they only appear random because our information about these systems are limited, insufficient to reveal an underlying, deterministic reality? Ever since the dawn of quantum mechanics, physicists have argued over this, from Einstein to Bohr and beyond.

Source: https://bigthink.com/

Jeff Bezos and Yuri Milner fund anti-aging start-up

Billionaires Jeff Bezos an Yuri Milner are reportedly funding a startup biotechnology firm with the aim of discovering a way to reverse aging.  Altos Labs was incorporated in the US and the UK earlier this year, and has raised at least $270million to look into the potential of cell reprogramming technology to turn back the clock in animals, and potentially, humans.

While little is known so far about Altos, early hires give an indication of the kinds of anti-aging techniques the lab might be looking into. They include Dr. Shinya Yamanaka, who pioneered researched into cell reprogramming, earning him the 2012 Nobel Prize for the research. He discovered that by adding just four specific proteins to cells, they can be instructed to revert back into an earlier state with the properties of embryonic stem cells that make up building blocks of new animal life.

He will serve as an unpaid advisor on Altosscientific advisory board, according to MIT Technology Review, which reported on Altos’ formation.

Source:  https://www.dailymail.co.uk/

Nobel Chemistry Prize Awarded For CRISPR ‘NanoScissors’

A humbling lesson of science is that, even when it comes to many of humanity’s most brilliant inventions, nature got there first. The 2020 selection for the Nobel Prize in Chemistry goes to two scientists who share credit for identifying and developing a revolutionary method of genome editing — one that has allowed researchers to modify and investigate the genomes of microbial, plant and animal cells with an ease, precision and effectiveness that would have been unfathomable even a decade ago. Yet the technology that came out of their work, revolutionary as it is, springs from an innovation that first evolved in bacteria, probably more than a billion years ago, and went unnoticed until recently.

Emmanuelle Charpentier (right) and Jennifer Doudna (left) have been awarded the 2020 Nobel Prize in Chemistry for their development of CRISPR/Cas9 genetic editing.

Emmanuelle Charpentier of the Max Planck Unit for the Science of Pathogens Institute for Infection Biology and Jennifer Doudna of the University of California, Berkeley have been recognized for their work on CRISPR/Cas9 genome editing — a technique routinely called CRISPR for short and often referred to as “genetic scissors.” This award marks the first time that two women have been award a Nobel Prize for science.

In a seminal 2012 paper, Charpentier and Doudna showed that key components of the ancient immune system found in bacteria and archaea could be retooled to edit DNA, to essentially “rewrite the code of life,” as the Nobel committee put it this morning.

In the eight years since, the discovery has transformed the life sciences, making genome editing commonplace in laboratories around the world. It has enabled researchers to probe the functions of genes at will, pushing the field of molecular biology ahead by leaps and bounds; to innovate new methods of plant breeding; and to develop promising new gene therapies, some now in clinical trials, for conditions such as sickle cell disease.

The Nobel committee’s selection will undoubtedly be greeted as controversial because of well-publicized disputes about the intellectual property associated with CRISPR. Virginijus Šikšnys of Vilnius University in Lithuania independently developed the idea of using these genetic features of bacteria as a genome-editing tool at about the same time as Charpentier and Doudna, and he has sometimes been honored alongside them. Two other scientists, Feng Zhang of the Massachusetts Institute of Technology and George Church of Harvard University, are also often credited as early co-discoverers and developers of CRISPR technology, and their exclusion will fuel arguments. However, no one in the scientific community would dispute that Charpentier and Doudna’s work laid the foundation for CRISPR’s prolific and game-changing use today.

Source: https://www.quantamagazine.org/