Highly Dangerous COVID Mutation Could Emerge in Cats

The recent suggestion that ministers may have to consider culling or vaccinating animals to prevent the coronavirus from picking up another dangerous mutation and jumping back to humans may sound like sudden panic, but it’s just part of a long debate among scientists.

Evidence that cats could be infected with SARS-CoV-2, the virus that causes COVID, emerged as early as April 2020 from Wuhan, China. Evidence that they could also transmit the infection to other cats under particular conditions appeared in the same month. Since then, infections have been confirmed in mink in Denmark and the Netherlands, in big cats in zoos, in dogs, ferrets and a range of other species. It’s also worth remembering that the source of SARS-CoV-2 is probably bats and that other species of wildlife may also be infectable.

Infection of some of these species with SARS-CoV-2 can cause actual disease, creating veterinary, welfare or conservation problems. However, transmission to or from companion animals that spend a lot of time in close contact with people also presents extra problems for trying to control a pandemic in humans. For example, if transmission between humans and cats happens easily, then controlling the pandemic in people might require measures to prevent it, and that might include vaccinating and quarantining cats.

There is good evidence for transmission from humans to cats but very little evidence for transmission from cats to humans. Nor is there much evidence for transmission between cats in normal situations (that is, not in a laboratory). At the moment, there’s no real reason to be concerned that infections in cats are a major problem. You’re at much greater risk from your family and friends with COVID than from their cats, although you should take normal hygiene precautions you use to reduce the risks of catching other diseases (such as toxoplasmosis) from cats.

Source: https://theconversation.com

Spread Of Mutated Coronavirus In Danish Mink

Denmark set off alarm bells this week with its announcement that it is culling the nation’s entire mink herd — the largest in the world — to stop spread of the SARS-CoV-2 virus in the prized fur species because of potentially dangerous mutationsInter-species jumps of viruses make scientists nervous — as do suggestions of potentially significant mutations that result from those jumps. In this case, Danish authorities say they’ve found some genetic changes that might undermine the effectiveness of Covid-19 vaccines currently in development. But is this latest twist in the Covid-19 saga reason to be deeply concerned?

This hits all the scary buttons,” noted Carl Bergstrom, an evolutionary biologist at the University of Washington. But Bergstrom and others argued that while the virus’s penchant for infecting mink bears watching, it isn’t likely to lead to a nightmare strain that is more effective at infecting peoplethan the current human virus.

I don’t believe that a strain which gets adapted to mink poses a higher risk to humans,” said Francois Balloux, director of University College London’s Genetics Institute. “We can never rule out anything, but in principle it shouldn’t. It should definitely not increase transmission. I don’t see any good reason why it should make the virus more severe,” he said.

Let’s take a look at what’s known about the Danish situation, why inter-species jumps make scientists nervous, whether the mutations are likely to affect vaccine effectiveness, and why Balloux thinks this situation is “fantastically interesting.” Denmark is the world’s largest producer of mink — by some estimates 40%. Unfortunately, mink are susceptible to the SARS-2 virus, a fact that came to light in April when the Netherlands reported outbreaks on mink farms there. Infected humans who work in the farms transmit the virus to captive minks, which are housed in close quarters ideal for rapid transmission from mink to mink.

 

Occasionally, the mink infect people — a phenomenon recorded in both the Netherlands and in Denmark. In a statement, the Danish Ministry of Environment and Food said the country would cull its entire herd — estimated to be about 17 million animals — after finding mutations in the viruses from the mink that it believes would allow those viruses to evade the immune protection generated by Covid-19 vaccines.

Source: https://www.statnews.com/