How to Grow Fully Functioning Hair Follicles
October 26, 2022
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Posted by admin
We can add functional mouse hair follicles to body parts that scientists have successfully grown in the lab, outside the body. Using cells obtained from embryonic mice, for the first time researchers were able to produce hair follicle organoids – small, simple versions of an organ – that grew hair.
Moreover, they were able to influence the pigmentation of the hair; and, when the follicles were transplanted into living hairless mice, they continued to function across multiple hair growth cycles. This research, the team says, could help aid efforts to treat hair loss, as well as provide alternative models to animal testing and drug screening.
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Categories: Uncategorized
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Tags: alopecia, baldness, cells, embryo, epidermis, hair, hair follicle organoids, hair follicles, hair loss, mesenchyme, morphogenesis, skin, stem cells, Yokohama National University
The NOTCH2NL genes are particularly active in the reservoir of neural stem cells of the cerebral cortex, the brain’s outer layer responsible for the highest mental functions such as cognition, language, memory, reasoning and consciousness. The genes were found to delay development of cortical stem cells into neurons in the embryo, leading to the production of a higher number of mature nerve cells in this brain region.
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