Reversing Age To Treat Alzheimer’s, Cancer and Cardiac Risks

RNA sequencing and gene network data are used to identify candidate genes that could turn back the “transcriptome clock” that reflects the biological age of distinct human cell types.

Technology has the potential to treat major age-related diseases including cardiovascular disease, cardiovascular disease, and cancer. More than 150,000 people die each day across the globe, about two-thirds of them from age-related causes like cancer, neurodegenerative diseases, strokes, and cardiovascular disease. If the process of aging could be slowed or reversed, the incidence of these conditions would be dramatically reduced, and more humans would live longer, healthier lives. However, aging is a complex process involving multiple biological systems – there is no single biomarker for aging. Therefore, developing treatments that target the root causes of aging is very challenging. Ichor is a Validation Project at the Wyss Institute of Harvard that aims to address this problem using high-throughput genetic screening to identify networks of genes that are strongly implicated in aging processes and develop RNA-based therapies that can make old cells young again.

You must be logged in to view this content.