Articles from November 2022



Cancer Vaccine Yields Significant Tumor Regression

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice. This is according to a new research study published in the journal Cell, reported by investigators from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

According to the research findings, intravenous (IV) administration of the vaccine boosted the number of cytotoxic T cells capable of infiltrating and attacking tumor cells and engaged the innate immune system by inducing type I interferon. The innate immune response modified the tumor microenvironment, counteracting suppressive forces that otherwise would tamp down T-cell action. Modification of the tumor microenvironment was not found in mice that received the vaccine via subcutaneous administration (i.e. a needle injection into the skin).

You must be logged in to view this content.

How to Diagnose Alzheimer’s Before Symptoms Emerge

A large study led by Lund University in Sweden has shown that people with Alzheimer's disease can now be identified before they experience any symptoms. It is now also possible to predict who will deteriorate within the next few years. The study is published in Nature Medicine, and is very timely in light of the recent development of new drugs for Alzheimer's disease.

It has long been known that there are two proteins linked to Alzheimer’sbeta-amyloid, which forms plaques in the brain, and tau, which at a later stage accumulates inside brain cells. Elevated levels of these proteins in combination with cognitive impairment have previously formed the basis for diagnosing Alzheimer's.

Changes occur in the brain between ten and twenty years before the patient experiences any clear symptoms, and it is only when tau begins to spread that the nerve cells die and the person in question experiences the first cognitive problems. This is why Alzheimer's is so difficult to diagnose in its early stages”, explains Oskar Hansson, senior physician in neurology at Skåne University Hospital and professor at Lund University.

You must be logged in to view this content.

AI Tailors Artificial DNA

With the help of an AI, researchers at Chalmers University of Technology, Sweden, have succeeded in designing synthetic DNA that controls the cells’ protein production. The technology can contribute to the development and production of vaccines, drugs for severe diseases, as well as alternative food proteins much faster and at significantly lower costs than today.

How our genes are expressed is a process that is fundamental to the functionality of cells in all living organisms. Simply put, the genetic code in DNA is transcribed to the molecule messenger RNA (mRNA), which tells the cell’s factory which protein to produce and in which quantities.

You must be logged in to view this content.

Smart Bandage

Millions of people dealing with diseases and suppressed immune systems are often forced to deal with chronic wounds—often minor injuries that nonetheless take much longer to heal because of compromised health. In addition to vastly varying degrees of recovery, issues like diabetic ulcers are also incredibly expensive, with treatment for a single incident costing as much as $50,000. Overall, chronic injuries cost Americans $25 billion a year, but a remarkable new device could soon offer a much more effective and cost-efficient way to not only help patients heal, but do so better than ever before.

You must be logged in to view this content.

Nano-robot Antibodies to Fight Cancer

Scientists in Israel have created the first nano-robot antibodies designed to fight cancer. The first human trial for the new nano-robots will start soon, and it will determine just how effective the antibodies are. What is special about these particular antibodies, too, is that they are programmed to decide whether cells surrounding tumors are “bad” or “good.”

The trial is currently underway in Australia and if it goes according to plan, the nano-robot antibodies will be able to fight cells around tumors that can help the tumor while also boosting the capability of the cells inhibiting the growth of the cancerous cells. The antibodies were invented by Professor Yanay Ofran and are based on human and animal antibodies.

You must be logged in to view this content.

How to Defend Ukraine against Russian Missiles

UK has successfully test-fired its first high-powered, long-range laser weapon — putting its military one step closer to dramatically improving its defense against incoming threats.

[This] is the culmination of five years worth of effort … To get to a position where we’ve proven that the technology is effective is fantastically exciting,” said Ben Maddison, technical partner at the UK Ministry of Defence’s Defence Science and Technology Laboratory (Dstl).

You must be logged in to view this content.

New Vaccine against Arthritis

Researchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a painful autoimmune disease that cannot currently be cured. The findings, detailed in a paper published in the journal Proceedings of the National Academy of Sciences, represent a major breakthrough in the study of rheumatoid arthritis and autoimmune diseases in general.
One of the most common autoimmune diseases, rheumatoid arthritis occurs when the body’s immune system attacks and breaks down healthy tissue — most notably the lining of joints in the hands, wrists, ankles and knees. Some estimates suggest rheumatoid arthritis affects as much as 1% of the global population.

You must be logged in to view this content.

New Solar Energy Harvesting System Generates Power 24/7

A University of Houston professor is reporting on a new type of solar energy harvesting system called thermophotovoltaics (STPV) that breaks the efficiency record of all existing technologies. And no less important, it clears the way to use solar power 24/7.

You must be logged in to view this content.

First Cultivated Meat Approved By The FDA

A major milestone is currently underway in the realm of cultivated meat. Food scientists have spent decades of research and development crafting new meat to tackle the increasing demand for this produce, reduce environmental degradation, and support animal welfare (via CNN). Now, one company is swiftly on its way to producing some of the country's first cultured protein. Following its first pre-market consultation, the FDA has evaluated the safety of cultivated chicken created by Upside Foods and confirmed that there are no further questions at this time.

You must be logged in to view this content.

Chronic Back Pain: New Treatment Is 84% More Effective

Back pain is a common condition with numerous causes, including poor posture, overexertion, constant stress at work or at home, lack of exercise, and poor posture. For a considerable number of patients, the symptoms are chronic, meaning they last a long period or reoccur repeatedly. However, port and exercise therapy, when done properly, can provide alleviation.

You must be logged in to view this content.