Daily Archives: May 3, 2021
Dozens of volunteers have begun participation in initial trials for a pill that pharmaceutical company Pfizer hopes will be a cure for COVID-19 available later this year, the Daily Telegraph reported Saturday.
The trial is being held at two Pfizer locations, one in the US and the other in Belgium, and will involve up to 60 volunteers age 18-60. The trial will be split into three phases spread over 145 days, with an extra 28 days tacked on the end for “screening and dosing,” according to the report, and will include several overnight stays for the participants.
“If they have moved to this stage, they will be quietly optimistic,” Prof. Penny Ward, a visiting professor in pharmaceutical medicine at King’s College London, told the Telegraph.
“The question will be about how the drug is tolerated,” said Ward, who helped develop Tamil, an antiviral treatment against flu.
The first phase will look at how well the new drug is tolerated and if there are “significant side effects, and how people feel after taking it,” according to Pfizer documents cited by the British news outlet. The next phase will include multiple doses while the third will look into the influence of eating food at the same time.
For that part, participants could receive instructions such as to consume a high-fat breakfast of “two eggs fried in butter, two strips of pork bacon, two slices of toast with butter, 4 oz. of hash brown potatoes, and 8 oz. of whole milk,” all of which must be consumed in 20 minutes.
Volunteers have been warned that the drug has so far only been tested on animals, according to the Pfizer documents.