Daily Archives: October 7, 2019

Edible Sensor To Check Whether Drugs Have Been Taken

An ingestible sensor that enables health workers to check that patients have taken their medication could revolutionise tuberculosis treatment, particularly in developing countries, researchers believe. New ways to ensure TB patients comply with their treatment are desperately needed. Patients with the most straightforward form of the deadly infectious disease have to take a cocktail of drugs over a six-month period – and if they fail to stick to the regime, they risk the disease returning in a drug-resistant form.

In the study, published in in the journal Plos Medicinepatients in California were given a standard TB drug alongside an “ediblesensor, coated with minerals.  When ingested, the sensor communicates with a patch attached to the patient’s torso that in turn sends a message to a mobile phone. The data is then automatically uploaded to a secure, centralised computer for a health worker to check.

To avoid high treatment drop-out rates it is recommended that patients take their medication under the supervision of a health worker in a procedure called directly observed therapy (DOT). But this is time consuming – requiring a health worker to visit the patient at work or home or vice versa – as well as costly and inconvenient. But this new “wireless observed therapy” (WOT) avoids the need for daily visits and enables the patient to take the drugs in private and at a time that suits them.

Some 77 patients, who were no longer infectious but still needed to finish their course of treatment, took part in the study, carried out by researchers at the University of California San Diego (UCSD). A third followed the standard DOT model of care and two thirds followed the novel treatment. The study showed that WOT had a 99.3 per cent accuracy rate in recording adherence to treatment and all those patients on the wireless therapy wanted to continue with it after the trial had ended. All finished treatment and were cured of TB.

Sara Browne, lead author of the study and associate professor of infectious diseases at the UCSD, said the ingestible sensor gave patients more autonomy.

The system allows patients to determine how they want to take their pills with minimum interference. It preserves the highest standards of privacy but it also enables the health system to focus on people who need the most support,” she said.

Source: http://grantome.com/
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https://www.telegraph.co.uk/