Daily Archives: October 11, 2018

Molecular Baskets Swallow, Trap And Remove Toxic Compounds

Researchers have developed designer molecules that may one day be able to seek out and trap deadly nerve agents and other toxic compounds in the environment – and possibly in humans.

The scientists, led by organic chemists from The Ohio State University, call these new particlesmolecular baskets.” As the name implies, these molecules are shaped like baskets and research in the lab has shown they can find simulated nerve agents, swallow them in their cavities and trap them for safe removal.

In a new study published in Chemistry – A European Journal, the researchers took the first step in creating versions that could have potential for use in medicine.

Our goal is to develop nanoparticles that can trap toxic compounds not only in the environment, but also from the human body,” said Jovica Badjić, leader of the project and professor of chemistry and biochemistry at Ohio State.

The research focuses on nerve agents, sometimes called nerve gas, which are deadly chemical poisons that have been used in warfare.

In a study published last year in the Journal of the American Chemical Society, Badjić and his colleagues created molecular baskets with amino acids around the rims. These amino acids helped find simulated nerve agents in a liquid environment and direct them into the basket.

Source:  https://news.osu.edu/