“The in situ vaccine approach has broad implications for multiple types of cancer,” said lead author Joshua Brody, MD, Director of the Lymphoma Immunotherapy Program at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. “This method could also increase the success of other immunotherapies such as checkpoint blockade.”
Even when it seems unbelievable: this is a genuine photograph, in which nothing has been faked. The 20 carats gold foam is lighter than milk foam
“Building a complete city from the ground up, even on a small scale like this, is a unique opportunity to develop future technologies, including a digital operating system for the infrastructure.Google has also experimented with the creation of its own smart city through its Sidewalk Labs division. The company is hoping to transform a 12-acre plot in Toronto’s waterfront district into a smart city, with the first homes due to appear in 2023.
An artificial intelligence (AI) system can reduce false positives and false negatives in prediction of breast cancer and outperforms human readers, according to a study published online Jan. 1 in Nature.
“It was a huge achievement to have completely repellent surfaces, but to maximize the benefits of such surfaces, we needed to create a selective door that would allow beneficial elements to bond with those surfaces,” explains Tohid Didar of McMaster’s Department of Mechanical Engineering and School of Biomedical Engineering, the senior author of a paper that appears today in the journal ACS Nano.
“We’ve found that microbes collected from an old mouse have the capacity to support neural growth in a younger mouse,” said Prof Pettersson. “This is a surprising and very interesting observation, especially since we can mimic the neuro-stimulatory effect by using butyrate alone.”
There are a lot of different kinds of scaffolds to choose from, ranging from ceramic and metals to cellulose hydrogels. So what makes hybrid aerogels any better than other scaffolds? For one, they are half made of proteins (that’s the “hybrid” bit), which are eventually broken down by the body. The other half, silica, slowly melts away as orthosilicic acid, which is known to hasten wound healing. Their pore size can be controlled during the manufacturing process, making it easy to adapt them to different uses. They are also being tested as drug delivery systems, meaning that the material could be spiked with medicines or growth factors before using it as a scaffold.
Earlier this year, three research labs based out of Iran, Germany, and Austria got together and decided to fuse a very strong protein with a very light and porous aerogel. The very strong protein is silk fibroin, the stuff found in silkworm cocoons and used to make fancy fabrics. It makes the aerogel strong and just stiff enough to use for bone growth. With the raw materials ready, the scientists started with Phase I: make the hybrid aerogel. Throw a source of silica, silk fibroin, some acid and a touch of detergent into a pot. Bake for an hour and voilà! You have yourself a silica-silk fibroin hybrid aerogel.
Having made the material, they now moved to Phase II: check if the hybrid aerogels are in any way harmful to human cells. In fact, the cells seemed to really like the material. When the hybrid aerogel was placed in a dish containing bone cells, they readily grew on its surface, depositing the proteins and minerals required for bone growth along the way.
On to Phase III: implant the hybrid aerogel in mice and check if it stimulates bone regeneration. The researchers made small bone injuries in two groups of mice and implanted the hybrid aerogel in one of them. After 25 days, they saw that the mice with the implants showed faster and better healing than the mice without implants. The aerogel was not just allowing new bone to grow, but also making it grow faster than normal.
This ability of the hybrid aerogel to speed up bone regeneration places it on the forefront of new therapeutic technologies. Imagine having bone fractures healing in a span of days, as opposed to weeks. Or being able to tell a bone cancer patient that, “Yes, you have to cut out a section of their leg but it can be easily grown back, no worries.” Hybrid aerogels are possibly the biomaterial that could make such conversations a reality.
Source: https://massivesci.com/
“Thymic involution leads to the depletion of critical immune cell populations, […] and is linked to age‐related increases in cancer incidence, infectious disease, autoimmune conditions, generalized inflammation, atherosclerosis, and all‐cause mortalit,” he explains In the study paper recently published in the journal 
“This is the only planet right now that we know outside the solar system that has the correct temperature to support water, it has an atmosphere, and it has water in it—making this planet the best candidate for habitability that we know right now,” University College London astronomer 
“We have developed a core base technology that can effectively detect pain, which is necessary for developing future-type tactile sensor. As an achievement of convergence research by experts in nano engineering, electronic engineering, robotics engineering, and brain sciences, it will be widely applied on electronic skin that feels various senses as well as new human-machine interactions.” Jang explained.
“Obesity and type 2 diabetes can lead to very serious and potentially life-threatening conditions such as cancer, stroke and heart disease. There is a real need to find new medicines so we can improve and save the lives of many patients, said Tricia Tan, Professor of Practice (Metabolic Medicine & Endocrinology) at Imperial College London and lead author of the study. “Although this is a small study our new combination hormone treatment is promising and has shown significant improvements in patients’ health in only four weeks. Compared to other methods the treatment is non-invasive and reduced glucose levels to near-normal levels in our patients”, she adds.
The brain makes physical events happen by turning thoughts into action, sending instructions through the nervous system to organs, limb
